Let artist Drew Friedman introduce you:
This is a just completed privately commissioned portrait of "Schlitzie, the Pin Head", AKA Schlitzie Surtees, and born (possibly) Simon Metz, in the Bronx in 1901. Schlitzie had microlephaly, a disorder that gave him a small brain and skull, and the cognizance of a three year old. he stood about four feet and wore dresses (due to his incontinence), leading many people to speculate he was a woman.
Comics connoisseurs likely recognize "Schlitzie" as the real-life inspiration for Bill Griffith's legendary "Zippy the Pinhead."