The Human Brain in Space: Euphoria and the "Overview Effect" Experienced by Astronauts
When in space, astronauts have repeatedly reported inexplicable euphoria, a "cosmic connection" or an increased sensitivity to their place in the Universe. The experience sounds like the ultimate high, or the ultimate enlightening; it would appear that without trying, astronauts are able to attain a similar mental state as meditating Buddhist monks.
All the more reason to populate space. Never mind the Singularity -- when enough of us become "off-worlders" we will have jettisoned much of the territorial baggage that defines the present human condition. Space exploration and colonization aren't merely fruitful components of a transhuman future: they're essential aspects that will change what we are.
I can't think of a scarier prospect for the status quo.